Genetic Developmental Disorders

Photographs

 

  Down Syndrome

 

 

 

 

 

 Fragile X
 

 

 

 Turner
 

 

A teratogen is …

 

any environmental influence that adversely affects the normal development of the fetus.

 

  FAS

 

 

 

 

 

 


 

There are four different teratogen categories:

 

·     physical agents

·     metabolic conditions of the mother

·     infection

·    drugs and alcohol


 

 

 

 

 

 

 

 

 

 

A dramatic example of a teratogen is thalidomide. In the early 1960s it was shown that more than 7,000 women who took the anti-nausea drug thalidomide during their pregnancy had children with very short or absent arms and legs, the absence of ears, as well as heart and intestinal malformations.

 

 

 

 


 

Partial list of teratogens

Drugs and chemicals

Alcohol

Aminoglycosides

Aminopterin

Antithyroid agents

Bromine (pesticide)

Cortisone

Diethylstilbesterol (DES)

Diphenylhydantoin

Cocaine, Heroin

Lead

Methylmercury

Penicillamine

Retinoic acid (Isoretinoin, Accutane)

Tetracycline

Thalidomide

Trimethadione

Valproic acid

Warfarin

Physical agents

Infectious organisms

Metabolic conditions in the mother


 

 

 

 

 

 

 

 

More Resources

 

http://textbooks.brookespublishing.com/batshaw/chapters/01/links.htm